Akathisia and Restless Legs by Perminder Sachdev

By Perminder Sachdev

This quantity presents the 1st complete account of the medical and scientific points of akathisia and similar syndromes comparable to stressed legs syndrome (RLS), other kinds of motor restlessness, and neuroleptic-induced dysphoria. the main target is on drug-induced akathisia and its a number of subtypes. the writer explores its courting to the restlessness because of different neurological issues, offers a brand new synthesis of the pathophysiological mechanisms of akathisia, and gives arguments for brand spanking new operational standards for the study prognosis of drug-induced akathisia. techniques for the size of akathisia also are mentioned, as are remedy ways. The ebook can be fairly valuable for psychiatrists, neurologists, and different physicians looking a greater realizing of those disabling syndromes.

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An unexpected finding of the Cohen-Mansfield et al (1989) study was that the agitated behaviours were overall worse in the daytime. This is contrary to the literature supporting a 'sundowning' phenomenon in elderly individuals with cognitive impairment. 3%) elderly nursing home residents. A closer examination of the Cohen-Mansfield et al data suggests that a proportion of their patients (14%) had more agitation during the evening shift, although there was a subgroup of 17% that was worse dur- 32 Introduction ing the day.

Some earlier studies (eg, Hordern, 1965; Rosenthal and Klerman, 1966; Rosenthal and Gudeman, 1967) demonstrated a significant positive loading for endogeneity, while others reported a weak relationship (Hamilton and White, 1959; Kiloh and Garside, 1963; Carney et al, 1965) and even a negative loading (Mendels and Cochrane, 1968). These differences were partly explained on the basis of the relationship of agitation to sex, with 30 Introduction studies that included only women showing a clear positive loading of agitation on the endogeneity factor (Mendels and Cochrane, 1968).

The term catatonia generally refers to a cluster of these motor symptoms, and it is important to recognize that in addition to schizophrenia, it may result from a number of organic mental disorders. Anxiety disorders An anxious person may experience trembling, twitching and shakiness as well as become restless both physically and mentally. The motor hyperactivity is typically associated with autonomic arousal and vigilance, as well as a subjective experience of unrealistic anxiety and worry. In an acute anxiety or panic episode, the individual is often pacing restlessly, moving arms and legs aimlessly and complaining loudly of inner turmoil.

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